※ 本文為 MindOcean 轉寄自 ptt.cc 更新時間: 2021-11-27 13:08:06
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作者 標題 [新聞] Classification of Omicron (B.1.1.529):
時間 Sat Nov 27 03:22:23 2021
完整標題：Classification of Omicron (B.1.1.529): SARS-CoV-2 Variant of Concern
發稿單位：WHO
發稿時間：26 November 2021
原文連結：https://www.who.int/news/item/26-11-2...-sars-cov-2-variant-of-concern
Classification of Omicron (B.1.1.529): SARS-CoV-2 Variant of Concern The Technical Advisory Group on SARS-CoV-2 Virus Evolution (TAG-VE) is an independent group of experts that periodically monitors and evaluates the ev ...
The Technical Advisory Group on SARS-CoV-2 Virus Evolution (TAG-VE) is an independent group of experts that periodically monitors and evaluates the evolution of SARS-CoV-2 and assesses if specific mutations and combinations of mutations alter the behaviour of the virus. The TAG-VE was convened on 26 November 2021 to assess the SARS-CoV-2 variant: B.1.1.529.
The B.1.1.529 variant was first reported to WHO from South Africa on 24 November 2021. The epidemiological situation in South Africa has been characterized by three distinct peaks in reported cases, the latest of which was predominantly the Delta variant. In recent weeks, infections have increased steeply, coinciding with the detection of B.1.1.529 variant. The first known confirmed B.1.1.529 infection was from a specimen collected on 9 November 2021.
This variant has a large number of mutations, some of which are concerning. Preliminary evidence suggests an increased risk of reinfection with this variant, as compared to other VOCs. The number of cases of this variant appears to be increasing in almost all provinces in South Africa. Current SARS-CoV-2 PCR diagnostics continue to detect this variant. Several labs have indicated that for one widely used PCR test, one of the three target genes is not detected (called S gene dropout or S gene target
failure) and this test can therefore be used as marker for this variant, pending sequencing confirmation. Using this approach, this variant has been detected at faster rates than previous surges in infection, suggesting that this variant may have a growth advantage.
There are a number of studies underway and the TAG-VE will continue to evaluate this variant. WHO will communicate new findings with Member States and to the public as needed.
Based on the evidence presented indicative of a detrimental change in COVID-19 epidemiology, the TAG-VE has advised WHO that this variant should be designated as a VOC, and the WHO has designated B.1.1.529 as a VOC, named Omicron.
As such, countries are asked to do the following:
enhance surveillance and sequencing efforts to better understand circulating SARS-CoV-2 variants.
submit complete genome sequences and associated metadata to a publicly available database, such as GISAID.
report initial cases/clusters associated with VOC infection to WHO through the IHR mechanism.
where capacity exists and in coordination with the international community, perform field investigations and laboratory assessments to improve understanding of the potential impacts of the VOC on COVID-19 epidemiology, severity, effectiveness of public health and social measures, diagnostic methods, immune responses, antibody neutralization, or other relevant characteristics.
Individuals are reminded to take measures to reduce their risk of COVID-19, including proven public health and social measures such as wearing well-fitting masks, hand hygiene, physical distancing, improving ventilation of indoor spaces, avoiding crowded spaces, and getting vaccinated.
For reference, WHO has working definitions for SARS-CoV-2 Variant of Interest (VOI) and Variant of Concern (VOC).
A SARS-CoV-2 VOI is a SARS-CoV-2 variant:
with genetic changes that are predicted or known to affect virus characteristics such as transmissibility, disease severity, immune escape, diagnostic or therapeutic escape; AND
that has been identified as causing significant community transmission or multiple COVID-19 clusters, in multiple countries with increasing relative prevalence alongside increasing number of cases over time, or other apparent epidemiological impacts to suggest an emerging risk to global public health.
A SARS-CoV-2 VOC is a SARS-CoV-2 variant that meets the definition of a VOI (see above) and, through a comparative assessment, has been demonstrated to be associated with one or more of the following changes at a degree of global public health significance:
increase in transmissibility or detrimental change in COVID-19 epidemiology; OR
increase in virulence or change in clinical disease presentation; OR
decrease in effectiveness of public health and social measures or available diagnostics, vaccines, therapeutics
初步證據指，Omicron 比其他變種病毒有更高再感染風險。
Omicron 整體有 50 個基因突變，當中用以感染人類細胞的刺突蛋白則有逾 30 種基因突變
這應該是第一個用星座為名的變種了
Omicron UMa，ο Ursae Majoris, ο UMa是在北天拱極星座大熊座內的一個恆星系統
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→ : 直接跳過nu跟xi1F 104.32.190.245 美國 11/27 03:22
推 : 意思是這東西一個抵三個？2F 223.136.127.201 台灣 11/27 03:29
→ : 一個病毒變種有兩種命名方式,真的是考3F 114.38.6.11 台灣 11/27 03:58
→ : 驗記憶能力
→ : 驗記憶能力
推 : 其實omicron 仍然是希臘字母5F 203.204.33.58 台灣 11/27 04:05
→ : 只是明明前面還有Nu跟Xi的說
→ : 難道有什麼不可告人的原因嗎
→ : 只是明明前面還有Nu跟Xi的說
→ : 難道有什麼不可告人的原因嗎
→ : Omicron是第15個希臘字母，不是什麼恆星8F 104.32.190.245 美國 11/27 04:05
→ : 系統
→ : 系統
推 : CHO這次不按前例直接跳過Nu跟Xi10F 64.180.215.78 加拿大 11/27 04:16
推 : 看來真的是所謂的三倍嚴重？11F 223.136.127.201 台灣 11/27 04:22
→ : 因為想不到跳過Nu跟Xi的理由,只能想到12F 114.38.6.11 台灣 11/27 04:28
→ : 之前說過要用星座系統命名來解釋了
→ : 之前說過要用星座系統命名來解釋了
推 : 跳過了，所以等不到Xi了嗎？14F 140.116.21.126 台灣 11/27 04:32
推 : 等不到Xi了15F 61.231.59.70 台灣 11/27 04:46
推 : 嘖 果然很who 直接跳過xi 又怕做得太16F 114.43.193.55 台灣 11/27 04:52
→ : 明顯 乾脆連nu也跳過
→ : 明顯 乾脆連nu也跳過
推 : 用xi的話維尼會氣噗噗18F 36.226.75.125 台灣 11/27 05:55
推 : 要人家不要用地名污名化自己搞得命名系統19F 114.136.194.120 台灣 11/27 06:08
→ : 還這麼沒邏輯(誤
→ : 還這麼沒邏輯(誤
推 : 看一下外國論壇，大家說是因為Nu 跟new發21F 88.130.49.139 德國 11/27 06:24
→ : 音一樣易搞混吧。
→ : 音一樣易搞混吧。
→ : 那Xi又會跟啥搞混(誤23F 114.136.194.120 台灣 11/27 06:39
推 : WHO真的被把持了...哈哈哈...24F 122.121.186.196 台灣 11/27 06:44
推 : 跳過Xi真的覺得WHO自我審查25F 37.4.250.44 德國 11/27 07:02
→ : 一次跳過兩個比較不明顯
→ : 一次跳過兩個比較不明顯
推 : Xi xi xi xi27F 203.204.18.143 台灣 11/27 07:17
推 : 請縮短網址。28F 82.217.213.71 荷蘭 11/27 07:21
推 : 跳過Xi 真賤29F 36.226.76.234 台灣 11/27 08:18
推 : 看半天才知道跳過xi的原因...哈哈哈30F 123.110.0.102 台灣 11/27 08:21
推 : 不能叫Xi不然中國又要大喊乳滑了31F 61.223.184.139 台灣 11/27 08:41
推 : 跳過Xi 這什麼噁爛的操作啊 噁心CHO32F 36.239.222.253 台灣 11/27 08:48
推 : 當初用希臘字母就應該看到這個了吧33F 61.228.56.19 台灣 11/27 08:48
推 : 不xi 了不xi 了34F 223.136.53.144 台灣 11/27 09:13
推 : 命名還要避諱？！35F 42.73.118.117 台灣 11/27 09:16
推 : 新聞稿說Xi是常見姓氏避免區域歧視。Xi36F 36.237.184.123 台灣 11/27 09:27
→ : 哪是常見姓氏啊連在中國都不是…，除了
→ : 哪是常見姓氏啊連在中國都不是…，除了
→ : WHO真的很舔 哈哈38F 39.11.4.71 台灣 11/27 09:27
→ : 那頭維尼。39F 36.237.184.123 台灣 11/27 09:27
→ : 一打30的概念。無敵萬能鑰匙40F 180.217.140.154 台灣 11/27 09:34
推 : 真的很舔 另外這病毒怎麼唸（笨41F 49.216.236.145 台灣 11/27 10:17
推 : 歐米控42F 61.228.56.19 台灣 11/27 10:19
推 : 歐米加(大O)的弟弟-小O43F 122.118.24.200 台灣 11/27 10:32
推 : 一個音節本來就不適合，容易聽錯，造44F 220.129.152.47 台灣 11/27 11:08
→ : 成資訊錯誤
→ : 成資訊錯誤
推 : 跳過Xi(習），變歐米控-歐洲 美國 .46F 118.166.198.145 台灣 11/27 11:11
→ : ..好像很故意XD
→ : ..好像很故意XD
推 : 也可以用唸出各別英文字母來區分防聽錯48F 61.228.56.19 台灣 11/27 11:13
→ : 有沒有心而已
→ : 有沒有心而已
推 : 跳過習耶，這組織太噁心了吧50F 118.169.27.195 台灣 11/27 11:18
推 : 避免直呼皇上名諱不是很正常的事嗎51F 1.34.135.62 台灣 11/27 11:39
→ : Xi何時晉升世界皇帝了==52F 112.78.79.248 台灣 11/27 11:49
推 : 舔爆 不Xi53F 223.138.183.145 台灣 11/27 11:59
→ : 現在還搞避諱54F 1.34.215.122 台灣 11/27 12:09
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